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Aging and estrogen alter endothelial reactivity to reactive oxygen species in coronary arterioles

Endothelium-dependent, nitric oxide (NO)-mediated vasodilation can be impaired by reactive oxygen species (ROS), and this deleterious effect of ROS on NO availability may increase with aging. Endothelial function declines rapidly after menopause, possibly because of loss of circulating estrogen and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kang, Lori S., Chen, Bei, Reyes, Rafael A., LeBlanc, Amanda J., Teng, Bunyen, Mustafa, S. Jamal, Muller-Delp, Judy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119103/
https://ncbi.nlm.nih.gov/pubmed/21441309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00349.2010
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