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Myostatin from the heart: local and systemic actions in cardiac failure and muscle wasting

A significant proportion of heart failure patients develop skeletal muscle wasting and cardiac cachexia, which is associated with a very poor prognosis. Recently, myostatin, a cytokine from the transforming growth factor-β (TGF-β) family and a known strong inhibitor of skeletal muscle growth, has be...

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Detalhes bibliográficos
Main Authors: Breitbart, Astrid, Auger-Messier, Mannix, Molkentin, Jeffery D., Heineke, Joerg
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119101/
https://ncbi.nlm.nih.gov/pubmed/21421824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00200.2011
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