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Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathway
Chronic inhibition of phosphodiesterase-5 with sildenafil immediately after permanent occlusion of the left anterior descending coronary artery was shown to limit ischemic heart failure (HF) in mice. To mimic a more clinical scenario, we postulated that treatment with sildenafil beginning at 3 days...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119085/ https://ncbi.nlm.nih.gov/pubmed/21398594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00654.2010 |
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