FTY720 Reduces Post-Ischemic Brain Lymphocyte Influx but Does Not Improve Outcome in Permanent Murine Cerebral Ischemia

BACKGROUND: The contribution of neuroinflammation and specifically brain lymphocyte invasion is increasingly recognised as a substantial pathophysiological mechanism after stroke. FTY720 is a potent treatment for primary neuroinflammatory diseases by inhibiting lymphocyte circulation and brain immig...

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Autori principali: Liesz, Arthur, Sun, Li, Zhou, Wei, Schwarting, Sönke, Mracsko, Eva, Zorn, Markus, Bauer, Henrike, Sommer, Clemens, Veltkamp, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119049/
https://ncbi.nlm.nih.gov/pubmed/21701599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021312
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