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Causal graph-based analysis of genome-wide association data in rheumatoid arthritis

BACKGROUND: GWAS owe their popularity to the expectation that they will make a major impact on diagnosis, prognosis and management of disease by uncovering genetics underlying clinical phenotypes. The dominant paradigm in GWAS data analysis so far consists of extensive reliance on methods that empha...

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Hlavní autoři: Alekseyenko, Alexander V, Lytkin, Nikita I, Ai, Jizhou, Ding, Bo, Padyukov, Leonid, Aliferis, Constantin F, Statnikov, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118953/
https://ncbi.nlm.nih.gov/pubmed/21592391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-6-25
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