Activation of latent Kaposi's sarcoma-associated herpesvirus by demethylation of the promoter of the lytic transactivator

Kaposi's sarcoma-associated herpesvirus (KSHV) is strongly linked to Kaposi's sarcoma, primary effusion lymphomas, and a subset of multicentric Castleman's disease. The mechanism by which this virus establishes latency and reactivation is unknown. KSHV Lyta (lytic transactivator, also named KSHV/Rta...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Chen, Jiguo, Ueda, Keiji, Sakakibara, Shuhei, Okuno, Toshiomi, Parravicini, Carlo, Corbellino, Mario, Yamanishi, Koichi
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2001
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274437/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051004198
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