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Photon counting, censor corrections, and lifetime imaging for improved detection in two-photon microscopy

We present a high-speed photon counter for use with two-photon microscopy. Counting pulses of photocurrent, as opposed to analog integration, maximizes the signal-to-noise ratio so long as the uncertainty in the count does not exceed the gain-noise of the photodetector. Our system extends this impro...

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Detalhes bibliográficos
Main Authors: Driscoll, Jonathan D., Shih, Andy Y., Iyengar, Satish, Field, Jeffrey J., White, G. Allen, Squier, Jeffrey A., Cauwenberghs, Gert, Kleinfeld, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118755/
https://ncbi.nlm.nih.gov/pubmed/21471395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00649.2010
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