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Metabotropic glutamate receptor 5 regulates excitability and Kv4.2-containing K(+) channels primarily in excitatory neurons of the spinal dorsal horn

Metabotropic glutamate (mGlu) receptors play important roles in the modulation of nociception. Previous studies demonstrated that mGlu5 modulates nociceptive plasticity via activation of ERK signaling. We have reported recently that the Kv4.2 K(+) channel subunit underlies A-type currents in spinal...

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Detalhes bibliográficos
Main Authors: Hu, Hui-Juan, Gereau, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118753/
https://ncbi.nlm.nih.gov/pubmed/21451053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01050.2010
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