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Augmented O-GlcNAc Signaling Attenuates Oxidative Stress and Calcium Overload in Cardiomyocytes

O-linked β-N-acetylglucosamine (O-GlcNAc) is an inducible, dynamically cycling and reversible post-translational modification of Ser/Thr residues of nucleocytoplasmic and mitochondrial proteins. We recently discovered that O-GlcNAcylation confers cytoprotection in the heart via attenuating the forma...

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Main Authors: Ngoh, Gladys A., Watson, Lewis J., Facundo, Heberty T., Jones, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118675/
https://ncbi.nlm.nih.gov/pubmed/20798965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-010-0728-7
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