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Leishmania promotes its own virulence by inducing expression of the host immune inhibitory ligand CD200

Leishmania parasites infect macrophages, cells normally involved in innate defense against pathogens. L. amazonensis and L. major cause severe or mild disease, respectively, consistent with each parasite’s ability to survive within activated macrophages. The mechanisms underlying increased virulence...

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Detalhes bibliográficos
Main Authors: Cortez, Mauro, Huynh, Chau, Fernandes, Maria Cecilia, Kennedy, Kathleen A., Aderem, Alan, Andrews, Norma W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118640/
https://ncbi.nlm.nih.gov/pubmed/21669395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.04.014
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