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Effect of postdevelopmental myostatin depletion on myofibrillar protein metabolism

It is unclear whether the muscle hypertrophy induced by loss of myostatin signaling in mature muscles is maintained only by increased protein synthesis or whether reduced proteolysis contributes. To address this issue, we depleted myostatin by activating Cre recombinase for 2 wk in mature mice in wh...

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Détails bibliographiques
Auteurs principaux: Welle, Stephen, Mehta, Sangeeta, Burgess, Kerri
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118593/
https://ncbi.nlm.nih.gov/pubmed/21406613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00509.2010
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