Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue

Nicotinic acid (NA) has been used as a lipid drug for five decades. The lipid-lowering effects of NA are attributed to its ability to suppress lipolysis in adipocytes and lower plasma FFA levels. However, plasma FFA levels often rebound during NA treatment, offsetting some of the lipid-lowering effe...

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Detalhes bibliográficos
Main Authors: Oh, Young Taek, Oh, Ki-Sook, Choi, Yong Min, Jokiaho, Anne, Donovan, Casey, Choi, Sangdun, Kang, Insug, Youn, Jang H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118587/
https://ncbi.nlm.nih.gov/pubmed/21386057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00650.2010
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