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Macrolactonization of Peptide Thioesters Catalyzed by Imidazole and Its Application in the Synthesis of Kahalalide B and Analogues

[Image: see text] The macrolactonization of peptide thioester to yield cyclic depsipeptides was developed using imidazole as a catalyst. This strategy was applied to the synthesis of kahalalide B and its analogues.

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Autors principals: Li, Yangmei, Giulionatti, Marc, Houghten, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118573/
https://ncbi.nlm.nih.gov/pubmed/20426464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100596p
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