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APOE-4 Genotype and Neurophysiological Vulnerability to Alzheimer’s and Cognitive Aging

Many years before receiving a clinical diagnosis of Alzheimer’s disease (AD), patients experience evidence of cognitive decline. Recent studies using a variety of brain imaging technologies have detected subtle changes in brain structure and function in normal adults with a genetic risk for AD; thes...

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Detalhes bibliográficos
Main Authors: Bookheimer, Susan, Burggren, Alison
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118550/
https://ncbi.nlm.nih.gov/pubmed/19327032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.clinpsy.032408.153625
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