Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells

PURPOSE: Fyn is a member of the Src family of kinases that we have previously shown to be overexpressed in prostate cancer. This study defines the biological impact of Fyn inhibition in cancer using a PC3 prostate cancer model. EXPERIMENTAL DESIGN: Fyn expression was suppressed in PC3 cells using an...

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Detalhes bibliográficos
Main Authors: Jensen, Ana R., Saito, Y. David, Liao, Chuanhong, Dai, Jinlu, Keller, Evan T., Al-Ahmadie, Hikmat, Haché, Kelly Dakin, Usatyuk, Peter, Sievert, Margarit, Paner, Gladell P., Yala, Soheil, Cervantes, Gustavo M., Natarajan, Viswanathan, Salgia, Ravi, Posadas, Edwin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118405/
https://ncbi.nlm.nih.gov/pubmed/21364031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1264
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