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Kernel density weighted loess normalization improves the performance of detection within asymmetrical data

BACKGROUND: Normalization of gene expression data has been studied for many years and various strategies have been formulated to deal with various types of data. Most normalization algorithms rely on the assumption that the number of up-regulated genes and the number of down-regulated genes are roug...

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Detalhes bibliográficos
Main Authors: Hsieh, Wen-Ping, Chu, Tzu-Ming, Lin, Yu-Min, Wolfinger, Russell D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118355/
https://ncbi.nlm.nih.gov/pubmed/21631915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-222
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