Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model

Intercellular adhesion molecule-1 (ICAM-1) in cerebral vascular endothelium induced by ischemic insult triggers leukocyte infiltration and inflammatory reaction. We investigated the mechanism of hypothermic suppression of ICAM-1 in a model of focal cerebral ischemia. Rats underwent 2 hours of middle...

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Главные авторы: Choi, Jung Sook, Park, Jaechan, Suk, Kyoungho, Moon, Cheil, Park, Yong-Ki, Han, Hyung Soo
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE-Hindawi Access to Research 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118291/
https://ncbi.nlm.nih.gov/pubmed/21716663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/846716
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