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Local gene transfer of tissue factor pathway inhibitor regulates intimal hyperplasia in atherosclerotic arteries

Tissue factor (TF), the initiator of blood coagulation and thrombosis, is up-regulated after vascular injury and in atherosclerotic states. Systemic administration of recombinant TF pathway inhibitor (TFPI) has been reported to decrease intimal hyperplasia after vascular injury and also to suppress...

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Autors principals: Zoldhelyi, Pierre, Chen, Zhi-Qiang, Shelat, Harnath S., McNatt, Janice M., Willerson, James T.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC31182/
https://ncbi.nlm.nih.gov/pubmed/11274432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061004098
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