Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: Role of uric acid accumulation in gemcitabine-induced MICA/B expression

BACKGROUND: Major histocompatibility complex class I-related chain A and B (MICA/B) are two stress-inducible ligands that bind the immunoreceptor NKG2D and play an important role in mediating the cyotoxicity of NK and T cells. In this study, we sought to study MICA/B expression in pancreatic cancer...

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Detalhes bibliográficos
Main Authors: Xu, Xiulong, Rao, Geetha S, Groh, Veronika, Spies, Thomas, Gattuso, Paolo, Kaufman, Howard L, Plate, Janet, Prinz, Richard A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118197/
https://ncbi.nlm.nih.gov/pubmed/21605422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-194
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