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The mRNA for a proteinase inhibitor related to the HI-30 domain of inter-alpha-trypsin inhibitor also encodes alpha-1-microglobulin (protein HC).

Inter-alpha-trypsin inhibitor (ITI) is a 180 kd serine proteinase inhibitor found in human serum. Treatment of 180 kd ITI with trypsin releases a 30 kd fragment (HI-30) which contains the anti-proteolytic activity of the high molecular weight form. We have isolated a cDNA clone from a human liver li...

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Detalhes bibliográficos
Main Authors: Kaumeyer, J F, Polazzi, J O, Kotick, M P
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC311818/
https://ncbi.nlm.nih.gov/pubmed/2430261
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