Time-dependent cytotoxic drugs selectively cooperate with IL-18 for cancer chemo-immunotherapy

BACKGROUND: Time-dependent chemotherapeutic agents can selectively target tumor cells in susceptible phases of the cell cycle however a fraction of tumor cells in non-vulnerable cell cycle phases remain drug-resistant. Immunotherapy represents a promising approach to overcome the limitation of phase...

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Detalhes bibliográficos
Main Authors: Alagkiozidis, Ioannis, Facciabene, Andrea, Tsiatas, Marinos, Carpenito, Carmine, Benencia, Fabian, Adams, Sarah, Jonak, Zdenka, June, Carl H, Powell, Daniel J, Coukos, George
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118128/
https://ncbi.nlm.nih.gov/pubmed/21609494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-77
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