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Defect in regulated secretion of P-selectin affects leukocyte recruitment in von Willebrand factor-deficient mice
Stimulation of endothelial cells by various inflammatory mediators leads to release of Weibel–Palade bodies and therefore to exocytosis of both P-selectin (adhesion receptor for leukocytes) and von Willebrand factor (vWf) (platelet ligand). The potential role of vWf in leukocyte recruitment was inve...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31181/ https://ncbi.nlm.nih.gov/pubmed/11274431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061307098 |
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