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Whole Body Skeletal Muscle Transduction in Neonatal Dogs with AAV-9
Gene therapy of muscular dystrophy requires systemic gene delivery to all muscles in the body. Adeno-associated viral (AAV) vectors have been shown to lead to body-wide muscle transduction after a single intravascular injection. Proof-of-principle has been demonstrated in mouse models of Duchenne mu...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118043/ https://ncbi.nlm.nih.gov/pubmed/21194038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61737-982-6_21 |
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