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Independent contributions of neural and “higher-order” deficits to symptoms in Alzheimer’s disease: A latent variable modeling approach

BACKGROUND: Analytic models of Alzheimer’s disease (AD) tend to focus on one type of symptom and assume implicitly that no measurement error is present. These tendencies render changes in symptom domains difficult to model mathematically, although latent variable methods can accommodate both multipl...

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Detalhes bibliográficos
Main Authors: Tractenberg, Rochelle E., Aisen, Paul S., Weiner, Myron F., Cummings, Jeffrey L., Hancock, Gregory R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118012/
https://ncbi.nlm.nih.gov/pubmed/19595904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2006.08.001
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