Analysis of Proteasomal Proteolysis during the In Vitro Metacyclogenesis of Trypanosoma cruzi

Proteasomes are large protein complexes, whose main function is to degrade unnecessary or damaged proteins. The inhibition of proteasome activity in Trypanosoma cruzi blocks parasite replication and cellular differentiation. We demonstrate that proteasome-dependent proteolysis occurs during the cell...

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Bibliografiske detaljer
Main Authors: Cardoso, Josiane, Lima, Carla De Paula, Leal, Tiago, Gradia, Daniela F., Fragoso, Stênio P., Goldenberg, Samuel, De Sá, Renata Guerra, Krieger, Marco A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117861/
https://ncbi.nlm.nih.gov/pubmed/21698116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021027
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