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Epigenetic alterations in RASSF1A in human aberrant crypt foci

CpG island methylation (CIM) is an epigenetic mechanism for transcriptional silencing that occurs at various stages of colon tumorigenesis. CIM has been found in serrated adenomas and hyperplastic polyps. There is also evidence for hypermethylation in aberrant crypt foci (ACF) that are found in rese...

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Detalhes bibliográficos
Main Authors: Greenspan, Emily J., Jablonski, Melissa A., Rajan, Thiruchandurai V., Levine, Joel, Belinsky, Glenn S., Rosenberg, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117759/
https://ncbi.nlm.nih.gov/pubmed/16513682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgi373
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