Minocycline fails to modulate cerebrospinal fluid HIV infection or immune activation in chronic untreated HIV-1 infection: results of a pilot study

BACKGROUND: Minocycline is a tetracycline antibiotic that has been shown to attenuate central nervous system (CNS) lentivirus infection, immune activation, and brain injury in model systems. To initiate assessment of minocycline as an adjuvant therapy in human CNS HIV infection, we conducted an open...

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Bibliografiska uppgifter
Huvudupphovsmän: Ho, Emily L, Spudich, Serena S, Lee, Evelyn, Fuchs, Dietmar, Sinclair, Elizabeth, Price, Richard W
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117676/
https://ncbi.nlm.nih.gov/pubmed/21569420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-8-17
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