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Predicting Fixation Tendencies of the H3N2 Influenza Virus by Free Energy Calculation

Influenza virus evolves to escape from immune system antibodies that bind to it. We used free energy calculations with Einstein crystals as reference states to calculate the difference of antibody binding free energy (ΔΔG) induced by amino acid substitution at each position in epitope B of the H3N2...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Pan, Keyao, Deem, Michael W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117619/
https://ncbi.nlm.nih.gov/pubmed/21691431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct100540p
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