Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population

The protein tyrosine phosphatase nonreceptor 22 gene (PTPN22) is an important negative regulator of signal transduction through the T-cell receptors (TCR). Recently a single-nucleotide polymorphism (SNP) 1858 C/T within this gene was shown to be a risk factor for several autoimmune diseases, such as...

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Autors principals: Zhebrun, Daria, Kudryashova, Yulia, Babenko, Alina, Maslyansky, Alexei, Kunitskaya, Natalya, Popcova, Daria, Klushina, Alexandra, Grineva, Elena, Kostareva, Anna, Shlyakhto, Evgeny
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2011
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117451/
https://ncbi.nlm.nih.gov/pubmed/21467606
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