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Role of Metal Dyshomeostasis in Alzheimer Disease

Despite serving a crucial purpose in neurobiological function, transition metals play a sinister part in the aging brain, where the abnormal accumulation and distribution of reactive iron, copper, and zinc elicit oxidative stress and macromolecular damage that impedes cellular function. Alzheimer di...

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Autors principals: Bonda, David J., Lee, Hyoung-gon, Blair, Jeffrey A., Zhu, Xiongwei, Perry, George, Smith, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117398/
https://ncbi.nlm.nih.gov/pubmed/21298161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mt00074d
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