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An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data
Motivation: Prediction of synergistic effects of drug combinations has traditionally been relied on phenotypic response data. However, such methods cannot be used to identify molecular signaling mechanisms of synergistic drug combinations. In this article, we propose an enhanced Petri-Net (EPN) mode...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117391/ https://ncbi.nlm.nih.gov/pubmed/21685086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr202 |
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