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Mixed-model coexpression: calculating gene coexpression while accounting for expression heterogeneity
Motivation: The analysis of gene coexpression is at the core of many types of genetic analysis. The coexpression between two genes can be calculated by using a traditional Pearson's correlation coefficient. However, unobserved confounding effects may cause inflation of the Pearson's correl...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117390/ https://ncbi.nlm.nih.gov/pubmed/21685083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr221 |
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