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A cautionary note for retrocopy identification: DNA-based duplication of intron-containing genes significantly contributes to the origination of single exon genes

Motivation: Retrocopies are important genes in the genomes of almost all higher eukaryotes. However, the annotation of such genes is a non-trivial task. Intronless genes have often been considered to be retroposed copies of intron-containing paralogs. Such categorization relies on the implicit premi...

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Detalhes bibliográficos
Main Authors: Zhang, Yong E., Vibranovski, Maria D., Krinsky, Benjamin H., Long, Manyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117337/
https://ncbi.nlm.nih.gov/pubmed/21551137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr280
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