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Systematic exploration of error sources in pyrosequencing flowgram data

Motivation: 454 pyrosequencing, by Roche Diagnostics, has emerged as an alternative to Sanger sequencing when it comes to read lengths, performance and cost, but shows higher per-base error rates. Although there are several tools available for noise removal, targeting different application fields, d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Balzer, Susanne, Malde, Ketil, Jonassen, Inge
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117331/
https://ncbi.nlm.nih.gov/pubmed/21685085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr251
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