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Globin gene transcripts can utilize histone gene 3' end processing signals.

Deletion of the poly(A) site from the human alpha globin gene results in a defective gene that produces very little stable mRNA as compared to the intact gene, presumably due to the instability of the mRNA. However, if the Alpha poly(A) site is replaced by mouse histone H4 3' end processing sig...

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Autors principals: Whitelaw, E, Coates, A, Proudfoot, N J
Format: Artigo
Idioma:Inglês
Publicat: 1986
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC311717/
https://ncbi.nlm.nih.gov/pubmed/3463933
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