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Misincorporation by AMV reverse transcriptase shows strong dependence on the combination of template and substrate nucleotides.

We have carried out a systematic investigation of the efficiency of misincorporation by Avian Myeloblastosis Virus reverse transcriptase with all possible combinations of dNTP substrate, template nucleotide, and the nucleotide at the 3' terminus of the primer. A series of synthetic oligonucleot...

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Bibliographic Details
Main Authors: Skinner, J A, Eperon, I C
Format: Artigo
Language:Inglês
Published: 1986
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC311710/
https://ncbi.nlm.nih.gov/pubmed/2429257
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