Replication of the association between variants in the IDE-KIF11-HHEX harboring region on chromosome 10q and plasma amyloid β levels in Alzheimer’s disease

BACKGROUND AND OBJECTIVE: Genetic linkage and association studies in late-onset Alzheimer’s disease (LOAD) or LOAD endophenotypes have pointed to several candidate regions on chromosome 10q, among these the ~250kb LD block harboring the three genes IDE, KIF11 and HHEX. We explored the association be...

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Detalhes bibliográficos
Main Authors: Reitz, Christiane, Cheng, Rong, Schupf, Nicole, Lee, Joseph H., Mehta, Pankaj D., Rogaeva, Ekaterina, St George-Hyslop, Peter, Mayeux, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117070/
https://ncbi.nlm.nih.gov/pubmed/20724036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.07.005
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