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Mechanisms of ATP Release by Human Trabecular Meshwork Cells, the Enabling Step in Purinergic Regulation of Aqueous Humor Outflow

Our guiding hypothesis is that ecto-enzymatic conversion of extracellular ATP to adenosine activates A(1) adenosine receptors, reducing resistance to aqueous humor outflow and intraocular pressure. The initial step in this purinergic regulation is ATP release from outflow-pathway cells by mechanisms...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LI, ANG, LEUNG, CHI TING, PETERSON-YANTORNO, KIM, STAMER, W. DANIEL, MITCHELL, CLAIRE H., CIVAN, MORTIMER M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117029/
https://ncbi.nlm.nih.gov/pubmed/21381023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22715
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