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Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer

The estrogen receptor (ER) is a major target for the treatment of breast cancer cells. Genistein, a soy isoflavone, possesses a structure similar to estrogen and can both mimic and antagonize estrogen effects although at high concentrations it inhibits breast cancer cell proliferation. Hence, to enh...

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Detalhes bibliográficos
Main Authors: Marik, Radharani, Allu, Madhan, Anchoori, Ravi, Stearns, Vered, Umbricht, Christopher B, Khan, Saeed
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116930/
https://ncbi.nlm.nih.gov/pubmed/21389782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.10.15184
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