Plasmodium falciparum Merozoite Invasion Is Inhibited by Antibodies that Target the PfRh2a and b Binding Domains

Plasmodium falciparum, the causative agent of the most severe form of malaria in humans invades erythrocytes using multiple ligand-receptor interactions. The P. falciparum reticulocyte binding-like homologue proteins (PfRh or PfRBL) are important for entry of the invasive merozoite form of the paras...

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Main Authors: Triglia, Tony, Chen, Lin, Lopaticki, Sash, Dekiwadia, Chaitali, Riglar, David T., Hodder, Anthony N., Ralph, Stuart A., Baum, Jake, Cowman, Alan F.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116812/
https://ncbi.nlm.nih.gov/pubmed/21698217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002075
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