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Sensitive on-chip detection of a protein biomarker in human serum and plasma over an extended dynamic range using silicon photonic microring resonators and sub-micron beads(†)

We demonstrate a three-step assay on a silicon photonic microring resonator-based detection platform that enables the quantitation of the cardiac biomarker C-reactive protein (CRP) over a dynamic range spanning six orders of magnitude. Using antibody-modified microrings, we sequentially monitor prim...

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Detalhes bibliográficos
Main Authors: Luchansky, Matthew S., Washburn, Adam L., McClellan, Melinda S., Bailey, Ryan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116709/
https://ncbi.nlm.nih.gov/pubmed/21541438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1lc20231f
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