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Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase

Antigens of pathogenic microbes that mimic autoantigens are thought to be responsible for the activation of autoreactive T cells. Viral infections have been associated with the development of the neuroendocrine autoimmune diseases type 1 diabetes and stiff-man syndrome, but the mechanism is unknown....

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hiemstra, Hoebert S., Schloot, Nanette C., van Veelen, Peter A., Willemen, Sabine J. M., Franken, Kees L. M. C., van Rood, Jon J., de Vries, René R. P., Chaudhuri, Abhijit, Behan, Peter O., Drijfhout, Jan W., Roep, Bart O.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31166/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274421/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071050898
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