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p21-activated kinases in Erbb2-positive breast cancer: A new therapeutic target?
The activation of receptor tyrosine kinases, particularly ErbB2, has been linked to the genesis and progression of breast cancer. Two of the central signaling pathways activated by ErbB2 are the Ras/Raf-1/Mek/Erk pathway, which plays an important role in tumor cell growth and migration, and the PI3K...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116598/ https://ncbi.nlm.nih.gov/pubmed/21686266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.1.2.14109 |
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