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Iron-Catalyzed Asymmetric Epoxidation of β,β-Disubstituted Enones

The combination of Fe(OTf)(2) and novel phenanthroline ligands enables the catalytic asymmetric epoxidation of acyclic β,β-disubstituted enones which have been heretofore inaccessible substrate classes. The reactions provide highly enantioenriched α,β-epoxyketones (up to 92% ee) which are further co...

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Autors principals: Nishikawa, Yasuhiro, Yamamoto, Hisashi
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116448/
https://ncbi.nlm.nih.gov/pubmed/21553923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja201873d
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