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L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis

L-selectin mediates homing of lymphocytes to lymph nodes (LN). Transgenic mice that express rat insulin promoter regulated simian virus 40 Tag (RIP-Tag) develop large, local cancers that metastasize to liver but not LN. To test whether this lack of LN metastases reflects their absence from the circu...

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Detalhes bibliográficos
Main Authors: Qian, Fawn, Hanahan, Douglas, Weissman, Irving L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31164/
https://ncbi.nlm.nih.gov/pubmed/11274419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061633698
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