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Dynamic Expression of Notch Signaling Genes in Neural Stem/Progenitor Cells
In neural stem/progenitor cells, expression of the Notch effector Hes1, a transcriptional repressor, oscillates with a period of 2–3 h by negative feedback, and Hes1 oscillations induce the oscillatory expression of the proneural gene Neurogenin2 (Ngn2) and the Notch ligand gene Delta-like1 (Dll1)....
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Research Foundation
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116140/ https://ncbi.nlm.nih.gov/pubmed/21716644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2011.00078 |
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