Characterization of Gap Junction Remodeling in Epicardial Border Zone of Healing Canine Infarcts and Electrophysiological Effects of Partial Reversal by Rotigaptide

BACKGROUND: The border zone of healing myocardial infarcts is an arrhythmogenic substrate partly due to structural and functional remodeling of the ventricular gap junction protein, Connexin43 (Cx43). Cx43 in arrhythmogenic substrates is a potential target for antiarrhythmic therapy. METHODS AND RES...

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Autori principali: Macia, Ester, Dolmatova, Elena, Cabo, Candido, Sosinsky, Alexandra Z., Dun, Wen, Coromilas, James, Ciaccio, Edward J., Boyden, Penelope A., Wit, Andrew L., Duffy, Heather S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116056/
https://ncbi.nlm.nih.gov/pubmed/21493965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.110.959312
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