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Induction of MUC5AC Mucin by Conjugated Bile Acids in the Esophagus Involves the PI3K/AKT/AP-1 Pathway
BACKGROUND: Bile reflux contributes to the development of esophageal injury and neoplasia. MUC5AC mucin is absent in the normal squamous epithelium of the esophagus but strongly expressed in Barrett’s esophagus (BE). The aim of this study was to determine whether and how bile acids influence the exp...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116027/ https://ncbi.nlm.nih.gov/pubmed/24048786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25796 |
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