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Targeted Delivery of Mutant Tolerant Anti-Coxsackievirus Artificial MicroRNAs Using Folate Conjugated Bacteriophage Phi29 pRNA

BACKGROUND: Myocarditis is the major heart disease in infants and young adults. It is very commonly caused by coxsackievirus B3 (CVB3) infection; however, no specific treatment or vaccine is available at present. RNA interference (RNAi)-based anti-viral therapy has shown potential to inhibit viral r...

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Detalhes bibliográficos
Main Authors: Ye, Xin, Liu, Zhen, Hemida, Maged Gomaa, Yang, Decheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115994/
https://ncbi.nlm.nih.gov/pubmed/21698212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021215
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