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Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine.

DNA heptamers containing the mutagenic base analogue 2-aminopurine (AP) have been chemically synthesized and physically characterized. We report on the relative stabilities of base pairs between AP and each of the common DNA bases, as determined from heptamer duplex melts at 275 and 330 nm. Base pai...

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Main Authors: Eritja, R, Kaplan, B E, Mhaskar, D, Sowers, L C, Petruska, J, Goodman, M F
Formato: Artigo
Idioma:Inglês
Publicado: 1986
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC311597/
https://ncbi.nlm.nih.gov/pubmed/3737416
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